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Very nice Mike.

I wonder if ChatGPT is aware of new research on DMSO, previously hailed as a "miraculous cure" for all sorts of illness?

https://geoffpain.substack.com/p/dmso-gentoxicity-via-z-dna

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As I said, ChatGPT is functionally a sophist. You can get the answers you want according to your bias, but you may have to be clever about wording your prompts. Think of it as a very unusual database engine with an idiot/savant driving it (for now),

It is trained on a small subset of the world's machine readable data, biased by curators, biased by trainers, and biased by the controlling corporation. These in turn are probably answerable to an even more powerful and corrupt entity, sometimes working openly, sometimes hiding in the shadows -- of course, I may be a paranoid schizophrenic. ;-)

Explain the promise arising from recent research on the benefits of using DMSO for treatment, and cite your references.

ChatGPT said:

ChatGPT

Searched 5 sites

Recent research has shown promising potential for the use of dimethyl sulfoxide (DMSO) in treating various conditions, though more extensive clinical studies are needed to confirm its efficacy.

Pain and Inflammation Relief: DMSO has been found to reduce pain and inflammation when applied topically. Small studies suggest it may help in conditions like peripheral neuropathy, osteoarthritis, and post-surgical pain, though the results are not universally conclusive. The analgesic properties make DMSO a candidate for treating musculoskeletal and inflammatory conditions, especially in cases where other medications may not be effective.

Bladder Pain Syndrome (Interstitial Cystitis): DMSO is FDA-approved for treating interstitial cystitis, a condition characterized by chronic bladder pain. It is used in this context by being administered directly into the bladder, which has shown some success in providing relief. However, more research is needed to fully establish the long-term benefits and safety of this treatment.

Cancer Research: Preliminary laboratory studies have suggested that DMSO may inhibit the growth of certain cancer cells. While these findings are promising, they are based on in vitro research, and clinical trials in humans have not yet been conducted to substantiate its use in cancer therapy.

Other Potential Uses: DMSO is being explored for treating conditions like diabetic ulcers, amyloidosis, and even as a treatment to reduce complications from chemotherapy leaks (extravasation). However, these uses are based on small studies, and more comprehensive research is necessary to establish its effectiveness for these applications.

While DMSO shows potential in a variety of medical treatments, it is crucial to use medical-grade DMSO under professional supervision, as over-the-counter products may pose safety risks due to contamination and lack of regulation.

For further details, you can refer to these sources:

https://www.health.com/dmso-uses-benefits

https://www.mskcc.org/cancer-care/integrative-medicine/herbs/dimethylsulfoxide

https://link.springer.com/article/10.1007/s00403-018-1903-x

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OK, it went out to the internet without being asked to:

Explain the cautions arising from recent research on the hazards of using DMSO for treatment, and cite you references.

Recent research on the use of dimethyl sulfoxide (DMSO) highlights several safety concerns that should be considered before use:

Eye and Neural Toxicity: Early studies suggested DMSO could cause eye damage, and more recent animal studies have shown potential neural toxicity. The significance of these findings in humans is still uncertain, but caution is advised due to the risks of long-term exposure.

For more details, visit: https://www.mcgill.ca/oss/article/medical-research/dmso-not-cure-all-fdas-panic-over-it-birthed-myth

Risk of Contamination: Many over-the-counter DMSO products are industrial-grade, which may contain harmful contaminants. Medical-grade DMSO is purified for therapeutic use, but using industrial variants can pose health risks.

See more at: https://www.mskcc.org/cancer-care/integrative-medicine/herbs/dimethylsulfoxide

Adverse Side Effects: Common side effects include skin irritation, garlic-like breath odor, dry skin, and gastrointestinal discomfort. These side effects, though mild, can be bothersome, especially with regular use.

Read further at: https://www.mskcc.org/cancer-care/integrative-medicine/herbs/dimethylsulfoxide

Lack of Strong Clinical Evidence: Clinical trials on DMSO's effectiveness for conditions like arthritis or neuropathy are often flawed. Many studies lack proper controls, making it hard to confirm its efficacy.

More information can be found here: https://link.springer.com/article/10.1007/s00403-018-1903-x

DMSO is FDA-approved only for interstitial cystitis, so using it for other purposes without medical guidance is not recommended.

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I have seen a couple of posts from A Midwestern Doctor on DMSO and also your objections. I have not looked into it otherwise.

I think with ChatGPT, which only "scrapes" what has been written and incorporated into "the model", you can get different results demanding on the prompt. For instance, I can probably (have not tried it of course) tell it to give me a negative report on DMSO or a positive report. It would give very different results depending on how it was prompted. This is based on a lot of experimentation over the past little while. I think I did a post mentioning using it for sophistry.

As I noted in the article, I don't have the training to wade through highly technical articles, understand the background, and decipher the jargon and acronyms.

ChatGPT 4.0 seems only to query the internet upon direct request. That is my impression, and I expect to change in the near future. I can not speak to the situation with other LLM AI - there a myriad of them now.

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Thanks very much Mike. Experiments using ChatGPT in Australian was in the news today.

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Did you look at my post on the types of things that LLM AI like ChatGPT can do? A strange emergent phenomenon. It will be like no other technology we have seen in its impact, naysayers to the contrary. They lack imagination I fear. It will also help establish a control grid. Predictions are always a mug's game.

https://ephektikoi.substack.com/p/understanding-the-world-probing-the

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